Author
The University of Texas at AustinORCID 0000-0001-9618-338XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Chia‐Wei Chou, Selma Sinan, Hung‐Che Kuo…·Ilya J. Finkelstein
This study reveals the structural basis for Cas13d's target discrimination and activation through cryo-EM structures and kinetic analysis of matched and mismatched RNA targets.
Ryan S. McCool, Cory M. Acreman, Abigail E. Powell…·Jason S. McLellan
This study designs and characterizes a prefusion-stabilized EBV gB antigen, showing improved immunogenicity and structural insights for vaccine development.
Kuang Hu, Chia‐Wei Chou, Claus O. Wilke, Ilya J. Finkelstein
This study identifies distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons, showing they use CRISPR RNAs and alternative unguided mechanisms for gene transfer.
Hung‐Che Kuo, Joshua Prupes, Chia‐Wei Chou, Ilya J. Finkelstein
The paper introduces RNA-CHAMP, a platform to measure RNA binding specificity of CRISPR-Cas13d, revealing structural and sequence determinants of target recognition and enabling SNP detection in SARS-CoV-2 variants.
Scott Wesley Long, Randall J. Olsen, Paul A. Christensen…·James M. Musser
The paper sequences 320 SARS-CoV-2 genomes from Houston to study early pandemic spread, finding diverse origins and no evidence of more virulent strains.