Author

Jerome L Paul

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Evolutionary Biology· 1

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander G Fletcher· 1 shared Alexander RA Anderson· 1 shared Daniel Nichol· 1 shared Jacob G Scott· 1 shared Peter Jeavons· 1 shared Philip K Maini· 1 shared Robert A Bonomo· 1 shared Robert A Gatenby· 1 shared

Activity by Year

2015-2015 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperEvolutionary Biology

Alexander G Fletcher

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1 paper

Recent·Most cited

Exploiting evolutionary non-commutativity to prevent the emergence of bacterial antibiotic resistance

Daniel Nichol, Peter Jeavons, Alexander G Fletcher, Robert A Bonomo, Philip K Maini, Jerome L Paul, Robert A Gatenby, Alexander RA Anderson, Jacob G Scott

This paper develops a Markov Chain model to analyze antibiotic resistance emergence in E. coli and shows that drug sequencing can probabilistically steer populations away from resistance.

bioRxiv · Feb 10, 2015Evolutionary Biology