Author

Robert A Gatenby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Organism:E. coli· 1

Frequent Co-Authors

Alexander RA Anderson· 2 shared Alexander G Fletcher· 1 shared Daniel Nichol· 1 shared Derek S. Park· 1 shared Jacob G Scott· 1 shared Jerome L Paul· 1 shared Mark Robertson-Tessi· 1 shared Michael B Bonsall· 1 shared

Activity by Year

2015-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Alexander RA Anderson

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 13, 2018

The Goldilocks Window of Personalized Chemotherapy: An Immune Perspective

Derek S. Park, Mark Robertson-Tessi, Philip Maini…·Alexander RA Anderson

This study uses mathematical modeling to show that optimal chemotherapy scheduling must balance tumor reduction and immune preservation to maximize treatment efficacy.

DOI 10.1101/495184

statistical modeldrug response / drug discovery

𝕏 PostBluesky

Evolutionary BiologyPLOS Computational BiologyPeer-reviewedSep 11, 2015

Exploiting evolutionary non-commutativity to prevent the emergence of bacterial antibiotic resistance

Daniel Nichol, Peter Jeavons, Alexander G Fletcher…·Jacob G Scott

This paper develops a Markov Chain model to analyze antibiotic resistance emergence in E. coli and shows that drug sequencing can probabilistically steer populations away from resistance.

DOI 10.1371/journal.pcbi.1004493

E. colistatistical model

𝕏 PostBluesky