A human induced pluripotent stem cell toolbox for studying sex chromosome effects
Ruta Meleckyte, Wazeer Varsally, Jasmin Zohren, Jerry Eriksson, Tania Incitti, Linda M. Starnes, Amy Pointon, Ryan Hicks, Benjamin E. Powell, James M. A. Turner
The paper generates isogenic hiPSCs with controlled sex chromosomes to study sex differences and X-haploinsufficiency effects on gene expression.
Stem Cell Reports · Oct 16, 2025Peer-reviewedGenetics