Jasmin Zohren

The paper generates isogenic hiPSCs with controlled sex chromosomes to study sex differences and X-haploinsufficiency effects on gene expression.

The paper analyzes single-cell genomics and transcriptomics data from CRISPR-Cas9-edited human embryos to assess unintended editing outcomes and loss-of-heterozygosity.

The paper develops CRISPR-Cas9 tools to generate all-male mouse litters by targeting the Topoisomerase 1 gene with a bicomponent system.