Small molecule inhibitors of hnRNPA2B1-RNA interactions reveal a predictable sorting of RNA subsets into extracellular vesicles
Jessica Corsi, Pouriya Sharbatian Semnani, Daniele Peroni, Romina Belli, Alessia Morelli, Michelangelo Lassandro, Viktoryia Sidarovich, Valentina Adami, Chiara Valentini, Paolo Cavallerio, Julian Großkreutz, Fabrizio Fabbiano, Dajana Großmann, Andreas Hermann, Gianluca Tell, , Vito D’Agostino
This study identifies small molecule inhibitors of hnRNPA2B1-RNA interactions and shows they alter EV-RNA composition and paracrine signaling.
Nucleic Acids Research · Feb 21, 2025Peer-reviewedMolecular Biology