Author

Jessica Lynn Kersey

Indiana University Indianapolis

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

John J. TurchiiD· 1 shared Joy Garrett· 1 shared Jun WaniD· 1 shared Matthew R. JordaniD· 1 shared Sheng LiuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

John J. TurchiORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMay 13, 2026

PARP1 catalytic domain mutations drive high-level resistance to saruparib while preserving DNA damage response vulnerabilities

Matthew R. Jordan, Jessica Lynn Kersey, Joy Garrett…·John J. Turchi

This study identifies PARP1 catalytic domain mutations as a mechanism of high-level resistance to saruparib in BRCA1-deficient breast cancer cells, while retaining DDR vulnerabilities.

DOI 10.64898/2026.05.08.723870

humanwhole-genome sequencing

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