FMR1 loss results in early changes to intrinsic membrane excitability in human cellular models
Sara G. Susco, Mario A. Arias-García, Violeta G. López-Huerta, Amanda Beccard, Anne M. Bara, Jessica Moffitt, Justin A. Korn, Zhanyan Fu, Lindy E. Barrett
This study examines the effects of FMR1 loss on intrinsic membrane excitability in human cortical neurons using isogenic hPSC models, finding early and transient changes in electrophysiological properties.
Developmental Biology · Sep 22, 2020Peer-reviewedNeuroscience