Evolution of ivermectin resistance in the nematode model Caenorhabditis elegans: critical influence of population size and unexpected cross-resistance to emodepside
Jacqueline R. Hellinga, Barbora Trubenová, Jessica Wagner, Marc Borchert, Jürgen Krücken, Roland R. Regoes, Hinrich Schulenburg Y, Georg von Samson‐Himmelstjerna
This study shows that large population size accelerates ivermectin resistance in C. elegans, with unexpected cross-resistance to emodepside and sexual recombination playing a role.
Evolutionary Applications · Apr 1, 2026Peer-reviewedEvolutionary Biology