Author

Jacqueline R. Hellinga

Freie Universität BerlinORCID 0009-0004-7703-5516Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Barbora TrubenováiD· 2 shared Hinrich Schulenburg YiD· 2 shared Jürgen KrückeniD· 2 shared Roland R. RegoesiD· 2 shared Georg von Samson-Himmelstjerna· 1 shared Georg von Samson‐HimmelstjernaiD· 1 shared Jessica Wagner· 1 shared Marc Borchert· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersEvolutionary Biology

Barbora TrubenováORCID

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2 papers

Recent·Most cited

Evolutionary BiologyEvolutionary ApplicationsPeer-reviewedApr 1, 2026

Evolution of ivermectin resistance in the nematode model Caenorhabditis elegans: critical influence of population size and unexpected cross-resistance to emodepside

Jacqueline R. Hellinga, Barbora Trubenová, Jessica Wagner…·Georg von Samson‐Himmelstjerna

This study shows that large population size accelerates ivermectin resistance in C. elegans, with unexpected cross-resistance to emodepside and sexual recombination playing a role.

3 citationstop 1%

C. elegansexperimental assay

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Evolutionary BiologyProceedings of the Royal Society B Biological SciencesPeer-reviewedOct 1, 2025

Investigating the consequences of the mating system for drug resistance evolution in C. elegans

Barbora Trubenová, Jacqueline R. Hellinga, Jürgen Krücken…·Roland R. Regoes

This study uses a population genetic model to show that androdioecious C. elegans populations adapt rapidly to drug selection and exhibit high genetic diversity.

2 citations

C. elegansstatistical model

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