BiochemistrybioRxivPreprint
Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Huasong Ai, Zebin Tong, Zhiheng Deng…·Man Pan
This study determines the cryo-EM structures of RNF168/UbcH5c-Ub/nucleosome complexes to elucidate the mechanism of H2A K13/K15 site-specific ubiquitination.
DOI 10.1101/2024.01.02.573964