Author

Jia-Feng Liu

Center for Life SciencesPrimary ORCID profile (0000-0003-3301-7194 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Jia-feng LiuiD1 paper · Tsinghua University

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:proteomics· 1

Frequent Co-Authors

Bo ZhengiD· 1 shared Fa-Zhan Wang· 1 shared Nan XiaoiD· 1 shared Yi-Wen Zhang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 2 mutual co-author links

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1 shared paperMicrobiology

Bo ZhengORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 11, 2026

A proteostasis clock tunes bacterial dormancy by timing replication initiation

Fa-Zhan Wang, Yi-Wen Zhang, Jia-Feng Liu

This study shows that bacterial dormancy lag time is controlled by proteostasis, with DnaA sequestration in aggregates delaying replication initiation and extending dormancy.

1 citation

bacteria (other)proteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 24, 2026

Outer membrane stiffness gates multidrug tolerance

Nan Xiao, Bo Zheng, Jia-Feng Liu

The paper identifies outer membrane stiffness as a determinant of multidrug tolerance in E. coli by showing it limits antibiotic-induced envelope destabilization.

DOI 10.64898/2026.08.24.746625

E. coliexperimental assay

𝕏 PostBluesky