ImmunologyFrontiers in ImmunologyPeer-reviewed
Oncolytic Adenovirus Armed with cGAS Activates STING Pathway and Enhances Antitumor Immunity in Lung Cancer with Superior Combined Efficacy of PD-L1 Therapy
Qingwen Wang, Hua-wei Xu, Yusen Shi…·Yuan-Hui Fu
This study develops oncolytic adenoviruses expressing cGAS to activate the STING pathway and enhance antitumor immunity in lung cancer, showing improved efficacy when combined with PD-L1 therapy.
DOI 10.3389/fimmu.2026.1904206