Weidong Zhao

Oncolytic Adenovirus Armed with cGAS Activates STING Pathway and Enhances Antitumor Immunity in Lung Cancer with Superior Combined Efficacy of PD-L1 Therapy

This study develops oncolytic adenoviruses expressing cGAS to activate the STING pathway and enhance antitumor immunity in lung cancer, showing improved efficacy when combined with PD-L1 therapy.

Performance Attribution in pLM-Based Biological Relation Prediction

The paper evaluates pLM-based biological relation prediction models to determine the sources of their performance, finding that multiple information sources contribute and that aggregate metrics alone cannot establish mechanistic insights.

Computational reconstruction of hierarchical cis-regulatory networks reveals synergistic transcription control and disease-associated rewiring

ORIGAMI reconstructs cis-regulatory networks using multi-omics data and deep learning, revealing synergistic transcription control and disease-associated rewiring.

DeepSRFusion: a point cloud deep learning framework for super-resolution particle fusion

DeepSRFusion improves super-resolution particle fusion for structural biology by addressing rotational perturbations and sparse labeling with a self-supervised framework, achieving high resolution and speed.