An RBP-J-heparan sulfate-dependent gatekeeper directs macrophage fate between inflammatory regulation and osteoclastogenesis
Ting Zheng, Huanmeng Hao, Jialin Jiang, Zhangjie Wang, Miaomiao Li, Courtney Ng, Jian Liu, Ding Xu, Baohong Zhao
This study identifies an RBP-J-HS-dependent network that regulates macrophage fate between inflammation and osteoclastogenesis in response to TNF.
bioRxiv · Sep 7, 2026 · PreprintImmunology