Author

Jian Ma

Chengdu University of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:diffusion model· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Chang‐Yu HsiehiD· 1 shared David C. Schwartz· 1 shared Haiguang LiuiD· 1 shared Jiajia LiuiD· 1 shared Jialu WuiD· 1 shared Jianguo WeniD· 1 shared Junchi YaniD· 1 shared Lin Tang· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBioinformatics

Chang‐Yu HsiehORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Ophiuchus-Ab: A Versatile Generative Foundation Model for Advanced Antibody-Based Immunotherapy

Yiheng Zhu, Jian Ma, Mingze Yin, Jialu Wu, Lin Tang, Zhiyun Zhang, Qiuyi Li, Shikun Feng, Haiguang Liu, Tao Qin, Junchi Yan, Chang‐Yu Hsieh, Tingjun Hou

Ophiuchus-Ab is a generative foundation model for antibody design that captures inter-chain dependencies and predicts antibody properties like developability and binding affinity.

bioRxiv · Feb 4, 2026 · PreprintBioinformatics

A Cell Cycle-aware Network for Data Integration and Label Transferring of Single-cell RNA-seq and ATAC-seq

Jiajia Liu, Jian Ma, Jianguo Wen, Xiaobo Zhou

The paper introduces CCAN, a model that removes cell cycle effects from integrated single-cell multi-omics data while preserving cell type-specific variations, showing strong performance in downstream tasks.

Advanced Science · Jun 17, 2024Peer-reviewedBioinformatics

Allele-Specific Quantification of Structural Variations in Cancer Genomes

Yang Li, Shiguo Zhou, David C. Schwartz, Jian Ma

Weaver quantifies allele-specific structural variations and copy number alterations in aneuploid cancer genomes, showing high accuracy in simulation and real data.

bioRxiv · Apr 13, 2016Bioinformatics