BiophysicsThe Journal of Physical Chemistry LettersPeer-reviewed
Molecular mechanisms of dynamics-mediated effects of pathogenic missense mutations on Menin protein function
Qian Zhang, Yinghao Guo, Hao Wang…·Bin Sun
This study shows that pathogenic missense mutations affect Menin function through dynamic changes and allostery, not just structural destabilization.
DOI 10.1021/acs.jpclett.6c00647