PRMT5 deficiency disturbs Nur77 methylation to inhibit endometrial stromal cell differentiation in recurrent implantation failure
Zhiwen Cao, Xiaoying Wang, Yang Liu, Xinyi Tang, Min Wu, Xin Zhen, Nannan Kang, Lijun Ding, Jianxin Sun, Xinyu Cai, Haixiang Sun, Guijun Yan, Ruiwei Jiang
This study shows PRMT5 deficiency disrupts Nur77 methylation, impairing endometrial stromal cell differentiation and contributing to recurrent implantation failure.
bioRxiv · Feb 6, 2024 · PreprintCell Biology