Haixiang Sun

This study shows PRMT5 deficiency disrupts Nur77 methylation, impairing endometrial stromal cell differentiation and contributing to recurrent implantation failure.

This study introduces MGA-Seq, a method to detect multiple genomic abnormalities, and finds that focal amplification in tumors is heterogeneous and reveals ecDNA network architecture.

The paper maps temporal and spatial dynamics of follicle development in mice by analyzing single-cell and spatial transcriptomes, revealing distinct stromal cell populations with specific roles in follicle development.

The paper identifies circPTPN12 as a regulator of miR-21-5p and ΔNp63α in endometrial fibrosis, suggesting it as a therapeutic target.