Contribution of the novel oxazolidinone TBD09 (MK-7762) to regimens with bedaquiline and pretomanid in a mouse model of tuberculosis
Deepak V. Almeida, Paul J. Converse, Courtney Schill, Jin I. Lee, Micha Levi, Alexander Berg, Mdluli Khisi, Eric L. Nuermberger
This study evaluates TBD09's contribution to BPa-based tuberculosis regimens in mice, showing comparable bactericidal and sterilizing activity to linezolid with reduced toxicity.
bioRxiv · Sep 24, 2026 · PreprintMicrobiology