Author

Deepak V. Almeida

Johns Hopkins UniversityORCID 0009-0004-8907-1792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Eric L. NuermbergeriD· 3 shared Paul J. ConverseiD· 2 shared A. Elaaf MohamediD· 1 shared Alexander BergiD· 1 shared Andrew Jesse GarciaiD· 1 shared Brendon M. LeeiD· 1 shared Brian M. FordeiD· 1 shared Chris GreeningiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

Eric L. NuermbergerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Contribution of the novel oxazolidinone TBD09 (MK-7762) to regimens with bedaquiline and pretomanid in a mouse model of tuberculosis

Deepak V. Almeida, Paul J. Converse, Courtney Schill, Jin I. Lee, Micha Levi, Alexander Berg, Mdluli Khisi, Eric L. Nuermberger

This study evaluates TBD09's contribution to BPa-based tuberculosis regimens in mice, showing comparable bactericidal and sterilizing activity to linezolid with reduced toxicity.

bioRxiv · Sep 24, 2026 · PreprintMicrobiology

Contribution of telacebec to novel drug regimens in a murine tuberculosis model

Oliver D. Komm, Sandeep K. Tyagi, Andrew Jesse Garcia, Deepak V. Almeida, Yong Seok Chang, Si‐Yang Li, Jennie Ruelas Castillo, Paul J. Converse, Todd A. Black, Nader Fotouhi, Eric L. Nuermberger

This study evaluates telacebec's contribution to combination therapies against two M. tuberculosis strains in a murine model, finding synergistic effects against HN878 and antagonistic effects against H37Rv.

Antimicrobial Agents and Chemotherapy · Dec 9, 2024Peer-reviewedMicrobiology

The evolution of nitroimidazole antibiotic resistance in Mycobacterium tuberculosis

Brendon M. Lee, Liam K. Harold, Deepak V. Almeida, Livnat Afriat‐Jurnou, Htin Lin Aung, Brian M. Forde, Kiel Hards, Sacha J. Pidot, F. Hafna Ahmed, A. Elaaf Mohamed, Matthew C. Taylor, Nicholas P. West, Timothy Paul Stinear, Chris Greening, Scott A. Beatson, , Colin J. Jackson

This study identifies mutations in Mycobacterium tuberculosis that confer resistance to nitroimidazole antibiotics, highlighting the need for monitoring these mutations to manage antibiotic use.

PLoS Pathogens · Feb 7, 2020Peer-reviewedMolecular Biology