Dynamic Gating Mechanism of the b0,+AT-Mediated Arg Transport: Insights from ASMD Simulations
Qinjie Tang, Xing Zhamg, Xuhua Li, Jing Dong, Haojia Li, Youshen Wu, Zhiwei Yang, Lei Li, Xinzhe Yu, Lei Zhang, Shengli Zhang
This paper identifies residue W230 as a dynamic gate in b0,+AT that regulates arginine transport through side chain flipping, using molecular dynamics simulations.
bioRxiv · Jun 9, 2026 · PreprintBiophysics