Jingtong Liu

Rational and computation-assisted engineering of a compact and efficient StaCas9 genome editor

This study identifies StaCas9 as a compact and efficient CRISPR-Cas9 variant with improved genome editing capabilities, particularly for therapeutic applications.

Closely related type II-C Cas9 orthologs recognize diverse PAMs

The paper identifies type II-C Cas9 orthologs with diverse PAM recognition capabilities, enhancing allele-specific genome editing.