Genome-wide association and multi-omics functional screens reveal the genetic architecture of foveal development
Callum Hunt, Manjiri Patil, Hammad Syed, Ha-Jun Yoon, Tingting Yang, Vanessa Rodwell, Zhanhan Tu, Gail D. E. Maconachie, Kayesha Coley, Alvin Lirio, Nick R. G. Shrine, Richard J. Packer, Mahmoud R. Fassad, Riddhi Shenoy, Natalie Allcock, , Mervyn George Thomas
This paper identifies genetic variants and genes associated with foveal hypoplasia using GWAS and multi-omics data, and establishes a zebrafish model to study the condition.
medRxiv · Jun 12, 2026 · PreprintGenetic & Genomic Medicine