Mervyn George Thomas

This study identifies Drosophila orthologues of OCA-associated genes that regulate sleep and circadian rhythm through visual neurotransmission without affecting pigmentation.

This paper identifies genetic variants and genes associated with foveal hypoplasia using GWAS and multi-omics data, and establishes a zebrafish model to study the condition.

This study shows that reducing sAC activity restores pigmentation in OCA models and increases melanin synthesis, suggesting targeting melanosome pH as a therapeutic strategy for OCA and skin cancer risk.

The paper identifies a conserved transcriptional signature in monoaminergic neurons across Bilaterian species using single-cell transcriptomics and a novel integration method.

This study identifies 123 genome-wide significant loci associated with foveal pit depth, revealing new biological pathways and genes involved in human foveal development.