ImmunologybioRxivPreprint
A selective alternative pathway complement inhibitor for treatment of paroxysmal nocturnal hemoglobinuria
Hagen Sülzen, Hanna Tulmin, Miroslav Hájek…·Sebastian Zoll
This paper introduces SH-01, a novel recombinant protein that selectively inhibits the complement alternative pathway, showing efficacy in preventing PNH-related erythrocyte lysis and reduced infection risk compared to current treatments.