Mtf2 Safeguards Naïve Pluripotency by Restricting Trophectoderm Competence
Seong-Min Kim, S-A Lim, Seong-Kyun Lim, Yeon-Joon Chu, Jiwon Bu, Young-Woo Won, Keun-Tae Kim, Hanbyeol Kim, Cantas Alev, Murim Choi, Chul‐Hwan Lee, Hyuk‐Jin Cha
This study identifies Mtf2 as an epigenetic barrier that maintains naive pluripotency by restricting trophectoderm competence in embryonic stem cells.
bioRxiv · Jun 14, 2026 · PreprintDevelopmental Biology