Author

Seong-Kyun Lim

Seoul National University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Chul‐Hwan LeeiD· 2 shared Annapurna PoduriiD· 1 shared Cantas AleviD· 1 shared Deciphering Developmental Disorders Study· 1 shared Dohyun HaniD· 1 shared Hanbyeol KimiD· 1 shared Hoseok Seo· 1 shared Hyuk‐Jin ChaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

Chul‐Hwan LeeORCID

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2 papers

Recent·Most cited

Mtf2 Safeguards Naïve Pluripotency by Restricting Trophectoderm Competence

Seong-Min Kim, S-A Lim, Seong-Kyun Lim, Yeon-Joon Chu, Jiwon Bu, Young-Woo Won, Keun-Tae Kim, Hanbyeol Kim, Cantas Alev, Murim Choi, Chul‐Hwan Lee, Hyuk‐Jin Cha

This study identifies Mtf2 as an epigenetic barrier that maintains naive pluripotency by restricting trophectoderm competence in embryonic stem cells.

bioRxiv · Jun 14, 2026 · PreprintDevelopmental Biology

De novo HDAC3 variants leading to epigenetic machinery dysfunction are associated with a neurodevelopmental disorder

Jihoon G. Yoon, Seong-Kyun Lim, Hoseok Seo, Seungbok Lee, Jaeso Cho, Soo Yeon Kim, Hyun Yong Koh, Annapurna Poduri, Deciphering Developmental Disorders Study, Jung Min Ko, Dohyun Han, Jong‐Hee Chae, Chul‐Hwan Lee

This study identifies de novo HDAC3 variants in patients with neurodevelopmental disorders and shows they cause reduced HDAC activity, disrupted protein interactions, and impaired nuclear localization.

medRxiv · Jan 29, 2024 · PreprintGenetic & Genomic Medicine