Author

João Victor de Souza

Newcastle University

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

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Agnieszka K. BronowskaiD· 1 shared Elizabeth G. Canty‐LairdiD· 1 shared Emily JohnsoniD· 1 shared

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Agnieszka K. BronowskaORCID

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BiophysicsbioRxivPreprintApr 3, 2025

Molecular dynamics simulations reveal a mechanism of calcium homeostasis driving homotrimerisation and heterotrimerization of type I collagen

Emily Johnson, João Victor de Souza, Agnieszka K. Bronowska, Elizabeth G. Canty‐Laird

This study uses molecular dynamics simulations to show how calcium ions influence the formation of hetero- and homotrimers of type I collagen, explaining the conditions under which homotrimers form.

DOI 10.1101/2025.04.03.646381

mechanistic / dynamical modelprotein folding & dynamics

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