NeuroscienceNature CommunicationsPeer-reviewed
Cortical Overgrowth in a Preclinical Forebrain Organoid Model of CNTNAP2-Associated Autism Spectrum Disorder
Job O. de Jong, Ceyda Llapashtica, Matthieu Genestine…·Sander Markx
This study uses patient-derived forebrain organoids to investigate the effects of a CNTNAP2 mutation on cortical development, finding increased cell proliferation and differential gene expression associated with ASD.
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