HIV-1 latency reversing agents converge on phosphoregulation of nuclear protein complexes
Jocelyn J. Ni, Prashant Kaushal, Shipra Sharma, Sara K. Makanani, Yennifer Delgado, Sophie F. Blanc, Charles Ochieng’ Olwal, Immy A. Ashley, Doug Winters, Vivian Yang, Callie N. Phung, Kareem Alba, Evan Wynn, Jeffrey R. Johnson, Judd F. Hultquist, , Mehdi Bouhaddou
This study identifies phosphoregulation of nuclear protein complexes by HIV-1 latency-reversing agents, revealing shared mechanisms across different LRAs.
bioRxiv · Nov 13, 2025 · PreprintMicrobiology