Adipose mitochondrial metabolism controls body growth by modulating cytokine and insulin signaling
Shrivani Sriskanthadevan-Pirahas, Michael J. Turingan, Joel S. Chahal, Erin Thorson, Savraj Grewal
This study shows that reducing mitochondrial bioenergetics in Drosophila fat body accelerates body growth by enhancing systemic insulin signaling through inhibition of TNF/Eiger.
bioRxiv · Apr 12, 2021 · PreprintDevelopmental Biology