Developmental BiologybioRxivPreprint
Adipose mitochondrial metabolism controls body growth by modulating cytokine and insulin signaling
Shrivani Sriskanthadevan-Pirahas, Michael J. Turingan, Joel S. Chahal…·Savraj Grewal
This study shows that reducing mitochondrial bioenergetics in Drosophila fat body accelerates body growth by enhancing systemic insulin signaling through inhibition of TNF/Eiger.