Savraj Grewal

This study identifies a cytokine-mediated signaling pathway in Drosophila that coordinates systemic hypoxia tolerance, revealing sex-specific requirements and a regulatory role for HIF-1/sima.

This study shows that reducing mitochondrial metabolism in Drosophila hemocytes decreases body growth by altering cytokine and insulin signaling.

This study shows hypoxia delays Drosophila maturation by suppressing EGF signaling in the prothoracic gland, independent of HIF-1 alpha and PTTH.

This study identifies a cell-specific role for ribosomal function in the neuroendocrine control of Drosophila development by showing that serotonergic neuron ribosomes regulate ecdysone production.

This study shows that reducing mitochondrial bioenergetics in Drosophila fat body accelerates body growth by enhancing systemic insulin signaling through inhibition of TNF/Eiger.

This study shows that TORC1 modulation in Drosophila adipose tissue is essential for adapting to hypoxia, involving lipid droplet remodeling and survival.

This study identifies that Ras/ERK signaling promotes tRNA synthesis and growth in Drosophila by inhibiting the Pol III repressor Maf1.

This paper describes a method to measure protein synthesis in Drosophila larvae using puromycin labeling and shows it detects changes in response to genetic and environmental factors.