Genome-wide analysis of Schistosoma mansoni reveals population structure and praziquantel drug selection pressure within Ugandan hot-spot communities
John Vianney Tushabe, Duncan Berger, Stephen R. Doyle, Geetha Sankaranarayanan, Joel Serubanja, Prossy Kabuubi Nakawungu, Fred Besigye, Richard E. Sanya, Nancy E. Holroyd, Fiona Allan, Emily L. Webb, Alison M. Elliott, Matthew Berriman, James Anthony Cotton
The paper analyzes whole-genome sequences of Schistosoma mansoni from Ugandan fishing communities to assess population structure and genetic changes associated with praziquantel treatment.
bioRxiv · Jan 25, 2022 · PreprintGenomics