HIPPOCAMPAL TAU RELATED SIGNAL INDEXES HYPEREXCITABILITY AND NREM SLEEP MEMORY DYSFUNCTION IN TEMPORAL LOBE EPILEPSY
Thaera Arafat, Katharina Schiller, Jack Lam, Nicolás von Ellenrieder, Zhengchen Cai, Jordan DeKraker, Fatemeh Fadaie, Viviane Sziklas, Joelle Crane, Raúl Rodríguez‐Cruces, Robert Hopewell, Chris Hung-Hsin Hsiao, Gassan Massarweh, Jean‐Paul Soucy, Kjell Erlandsson, , Boris C. Bernhardt
This study links higher hippocampal 18F-MK6240 uptake in TLE to increased seizure burden, altered NREM sleep microstructure, and impaired memory.
bioRxiv · Sep 13, 2026 · PreprintNeuroscience