Jordan DeKraker

HIPPOCAMPAL TAU RELATED SIGNAL INDEXES HYPEREXCITABILITY AND NREM SLEEP MEMORY DYSFUNCTION IN TEMPORAL LOBE EPILEPSY

This study links higher hippocampal 18F-MK6240 uptake in TLE to increased seizure burden, altered NREM sleep microstructure, and impaired memory.

Hippocampal subfields support human novelty detection via distinct signals

The paper identifies distinct hippocampal subfield signals for novelty detection, showing CA1 supports local associative mismatch while subiculum supports global item-based matching.

HippoGenes: A robust workflow for subregional transcriptomic profiling of the human hippocampus

HippoGenes creates transcriptomic maps of the human hippocampus using spatial statistical models and the Allen Human Brain Atlas, enabling subregional gene expression analysis and disease-related molecular decoding.

Distinct spatial associations of adversity with hippocampal macro- and microstructure in early adolescence

The paper examines how different types of adversity relate to hippocampal macro- and microstructure in early adolescents, finding distinct spatial associations across brain regions.

A surface-intrinsic framework for topology-preserving hippocampal alignment and precision morphometry

This paper introduces a surface-intrinsic framework for hippocampal unfolding that improves alignment accuracy and morphology preservation compared to volumetric methods.

Selective convergence and graded divergence of hippocampal and amygdala subregions using functional connectivity

This study maps hippocampal and amygdala subregions using resting-state fMRI from 722 participants, revealing structured co-representation patterns and divergence in functional connectivity.

FUNCTIONAL FRAGMENTATION AND STRUCTURAL DRIVERS OF THALAMO-CORTICAL CIRCUITS IN TEMPORAL LOBE EPILEPSY

This study examines thalamo-cortical and thalamo-hippocampal functional connectivity in temporal lobe epilepsy, finding reduced connectivity in TLE patients and its association with seizure generalization and surgical outcomes.

Hierarchical Signatures of Language in the Human Brain

This study identifies hierarchical neural signatures of language by linking semantic and phonological processing to brain networks using fMRI, myelin measures, and AI models.

The electro-MICA toolbox for integrating electrophysiology within multimodal imaging and connectomics workflows

electro-MICA projects electrophysiological features onto cortical surfaces using numerical solutions to electromagnetic equations, outperforming conventional models in iEEG validation.

MICAFlow: Fast and Robust MRI Preprocessing Bridging Research Neuroimaging and Clinical Practice

MICAFlow provides a fast and robust MRI preprocessing pipeline that translates research workflows into clinical practice, achieving high registration accuracy and data reliability across diverse datasets.

Memory network activity flow failures in temporal and frontal lobe epilepsy

This study uses activity flow mapping to show reduced task activation prediction accuracy in TLE and FLE patients, linking intrinsic network dysconnectivity to memory impairments.

State dependent shifts in large scale functional topographies

The paper examines how cognitive states like resting and movie watching affect large-scale brain functional connectivity using fMRI data from the HCP and PNI datasets.

Geometry-Constrained Coupling Drives Critical Dynamics Across Neural Manifolds

This paper introduces a framework for geometry-constrained coupling between neural manifolds, showing how inter-manifold interactions reorganize dynamics and produce critical transitions in brain activity.

A unified imaging-histology framework for superficial white matter architecture studies in the human brain

The paper develops a computational framework to study superficial white matter organization using 3D histology and 7T MRI, finding high structural complexity in the first 2 mm below the cortical boundary and correlations with cortical geometry and connectivity.

MULTIMODAL GRADIENTS UNIFY LOCAL AND GLOBAL CORTICAL ORGANIZATION

This paper maps global cortical organization by integrating microstructural, connectivity, and functional data with cytoarchitectural maps, revealing a sensory-fugal gradient and functional diversity across brain areas.

Multimodal precision MRI of the individual human brain at ultra-high fields

The paper shares a multimodal 7T MRI dataset of ten healthy individuals, providing structural and functional brain data across multiple imaging modalities and parcellation scales.

From histology to macroscale function in the human amygdala

This study identifies subregional structure-function coupling in the human amygdala using histology and MRI, revealing two axes of microstructural variation linked to functional networks.

Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology

This study investigates how epilepsy-related mesiotemporal pathology reorganizes episodic and semantic memory systems using functional MRI in TLE patients and healthy controls.

Hippocampal connectivity patterns echo macroscale cortical evolution in the primate brain

This study compares hippocampal structure and function across humans and macaques to show conservation of micro- and macro-structure but evolutionary reconfiguration in functional connectivity.

Cerebral perfusion alterations in temporal lobe epilepsy: Structural underpinnings and network disruptions

This study investigates cerebral perfusion changes in temporal lobe epilepsy using multimodal imaging and finds widespread CBF reductions linked to structural and network disruptions.

Atypical connectome topography and signal flow in temporal lobe epilepsy

This study identifies atypical functional topography and reduced hierarchical signal flow in temporal lobe epilepsy, linked to microstructural white matter changes and cognitive impairments.

HippoMaps: Multiscale cartography of the human hippocampal formation

HippoMaps provides a toolbox and data warehouse for mapping and analyzing hippocampal data across multiple modalities and scales.

Mapping the Macrostructure and Microstructure of the in vivo Human Hippocampus using Diffusion MRI

This paper uses diffusion MRI and computational methods to map macro- and microstructural features of the human hippocampus, revealing distinct subfield characteristics and potential fiber pathway orientations.

Novel insights into hippocampal perfusion using high-resolution, multi-modal 7T MRI

This study measures hippocampal perfusion using 7T MRI and finds significant subfield differences, with CA1 having the lowest perfusion, influenced by vascular proximity and cytoarchitecture.

Evaluation of surface-based hippocampal registration using ground-truth subfield definitions

This paper introduces a surface-based hippocampal registration method that improves subfield alignment across different morphologies.

Organization of pRF size along the AP axis of the hippocampus is related to specialization for scenes

The paper examines pRF size along the AP axis of the hippocampus and finds it correlates with scene sensitivity, similar to surrounding MTL regions.

Atypical intrinsic neural timescales in temporal lobe epilepsy

This study identifies atypical intrinsic neural timescales in temporal lobe epilepsy, showing reduced timescales in multiple brain regions and high accuracy in classifying patients and lateralizing seizure foci.

Automated hippocampal unfolding for morphometry and subfield segmentation with HippUnfold

HippUnfold is an automated BIDS-App for hippocampal unfolding and subfield segmentation using deep learning and topological constraints, enabling individual-specific morphometric analysis.

DIFFERENTIAL MEMORY IMPAIRMENT ACROSS RELATIONAL DOMAINS IN TEMPORAL LOBE EPILEPSY

This study assesses memory impairments in temporal lobe epilepsy patients across episodic, semantic, and spatial domains using behavioral tests and statistical analysis.

Micapipe: a pipeline for multimodal neuroimaging and connectome analysis

Micapipe is an open pipeline for processing multimodal MRI data, generating structural and functional connectomes, geodesic distances, and microstructural profiles across multiple brain parcellations and surface spaces.