Author
Montreal Neurological Institute and HospitalORCID 0000-0002-2478-5872Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Thaera Arafat, Katharina Schiller, Jack Lam…·Boris C. Bernhardt
This study links higher hippocampal 18F-MK6240 uptake in TLE to increased seizure burden, altered NREM sleep microstructure, and impaired memory.
Jack Lam, Raúl Rodríguez‐Cruces, Thaera Arafat…·Boris C. Bernhardt
The paper presents an open dataset of cerebral tau deposition in young healthy adults using [18F]MK6240 PET to support imaging biomarker studies in non-geriatric populations.
Raúl Rodríguez‐Cruces, Jack Lam, Thaera Arafat…·Boris C. Bernhardt
This study finds increased tau deposition in TLE patients using PET imaging, linked to cognitive impairment and brain connectivity patterns.
Peter Kunach, Jaime Vaquer‐Alicea, Matthew S. Smith…·Sarah H. Shahmoradian
The paper determines the cryo-EM structure of Alzheimer's disease tau filaments bound by the PET ligand MK-6240, revealing key binding interactions that inform ligand design.