Andrea Bernasconi

This study examines how connector hubs in temporal lobe epilepsy patients reorganize compared to healthy controls, finding widespread hub reductions and new hub emergence in contralateral regions.

This study links higher hippocampal 18F-MK6240 uptake in TLE to increased seizure burden, altered NREM sleep microstructure, and impaired memory.

HippoGenes creates transcriptomic maps of the human hippocampus using spatial statistical models and the Allen Human Brain Atlas, enabling subregional gene expression analysis and disease-related molecular decoding.

This paper quantifies multiscale MRI changes in focal cortical dysplasia lesions and links them to macroscale brain organization patterns.

This study examines thalamo-cortical and thalamo-hippocampal functional connectivity in temporal lobe epilepsy, finding reduced connectivity in TLE patients and its association with seizure generalization and surgical outcomes.

The paper presents an open dataset of cerebral tau deposition in young healthy adults using [18F]MK6240 PET to support imaging biomarker studies in non-geriatric populations.

This study examines sex differences in structural brain alterations in common epilepsies using neuroimaging data from a large international cohort, finding some regional differences but no significant sex-by-diagnosis interactions.

The paper identifies a reproducible functional connectivity signature in temporal lobe epilepsy through a large-scale connectome-wide analysis.

The paper identifies patient-specific structural deviations and disease epicenters in temporal lobe epilepsy using multimodal MRI data, linking resection overlap with seizure freedom.

This study uses activity flow mapping to show reduced task activation prediction accuracy in TLE and FLE patients, linking intrinsic network dysconnectivity to memory impairments.

This study identifies patient-specific functional biomarkers in temporal lobe epilepsy using multimodal MRI data to predict clinical outcomes and guide precision therapeutics.

This paper reviews AI/ML applications in MRI for epilepsy, finding high accuracy in diagnosis and prediction but significant bias issues limiting clinical use.

The paper examines associations between epilepsy-related polygenic risk scores and brain morphology in children, finding PRS-related cortical thinning linked to structural patterns in TLE-HS patients.

This study finds increased tau deposition in TLE patients using PET imaging, linked to cognitive impairment and brain connectivity patterns.

The paper develops a computational framework to study superficial white matter organization using 3D histology and 7T MRI, finding high structural complexity in the first 2 mm below the cortical boundary and correlations with cortical geometry and connectivity.

The paper identifies structural and functional alterations in cortical regions associated with epileptic spikes and their connected networks using multimodal MRI and EEG.

This study investigates how epilepsy-related mesiotemporal pathology reorganizes episodic and semantic memory systems using functional MRI in TLE patients and healthy controls.

This study investigates cerebral perfusion changes in temporal lobe epilepsy using multimodal imaging and finds widespread CBF reductions linked to structural and network disruptions.

This study shows that pharmaco-resistant temporal lobe epilepsy causes a progressive shift in cortical excitation-inhibition balance, linked to cognitive impairments and seizure frequency.

This study identifies atypical functional topography and reduced hierarchical signal flow in temporal lobe epilepsy, linked to microstructural white matter changes and cognitive impairments.

This study examines age-related changes in grey and white matter in TLE patients across the adult lifespan, finding accelerated aging effects after age 55.

HippoMaps provides a toolbox and data warehouse for mapping and analyzing hippocampal data across multiple modalities and scales.

This study shows that a socio-affective mental training module increases hippocampal subfield volume and functional connectivity, correlating with reduced cortisol levels in healthy adults.

This study identifies reduced microstructural differentiation in TLE patients, linking it to cognitive dysfunction and network reorganization.

This study identifies atypical intrinsic neural timescales in temporal lobe epilepsy, showing reduced timescales in multiple brain regions and high accuracy in classifying patients and lateralizing seizure foci.

This study assesses memory impairments in temporal lobe epilepsy patients across episodic, semantic, and spatial domains using behavioral tests and statistical analysis.

This study examines the heritability of hippocampal functional and microstructural organisation in healthy adults using twin data and multimodal neuroimaging.

The paper shares a multimodal MRI dataset for studying multiscale brain organization, including connectomes and gradients from multiple imaging modalities.

The paper presents a whole-brain 3D myeloarchitectonic atlas based on historical histological data, validated with MRI markers and integrated into neuroimaging software.

This study identifies divergent patterns of atypical cortical asymmetry and regional atrophy in temporal lobe epilepsy using MRI data from a large multi-site cohort.