Fine Tuning Genetic Circuits via Host Context and RBS Modulation
Dennis Tin Chat Chan, Lena Winter, Johan Bjerg, Stina Krsmanovic, Geoff S. Baldwin, Hans Christopher Bernstein
This study fine-tunes a genetic toggle switch by varying host contexts and ribosome binding sites to optimize performance metrics like signaling strength and inducer sensitivity.
ACS Synthetic Biology · Jan 4, 2025Peer-reviewedSynthetic Biology