Geoff S. Baldwin

This study fine-tunes a genetic toggle switch by varying host contexts and ribosome binding sites to optimize performance metrics like signaling strength and inducer sensitivity.

This study investigates the chassis-effect in genetic switches across bacterial hosts, finding that physiological similarity correlates with toggle switch performance.

Galaxy-SynBioCAD provides an automated pipeline for synthetic biology design and engineering, achieving an 83% success rate in retrieving validated pathways.

The paper develops a modular toolset to improve the performance and standardization of electrogenetic systems for spatiotemporal gene expression control.

The paper introduces basicsynbio, an open-source software tool for designing and assembling DNA sequences using the BASIC method, and presents the BASIC SEVA collection of vectors.

This paper introduces mARi, a modular RNA interference system for multiplexed gene regulation in E. coli, demonstrating its robustness and orthogonality across different genetic contexts.

The paper evaluates three OD calibration protocols for bacterial cell count estimation and recommends serial dilution of silica microspheres for its precision and compatibility with flow cytometry.

DNA-BOT enables low-cost, automated DNA assembly of 88 constructs with high accuracy and affordability.