Cell BiologyAmerican Journal of Physiology-Cell PhysiologyPeer-reviewed
Insulin-Regulated Actin Dynamics is Disrupted in a Human Keratinocyte Model of Hailey Hailey Disease
Ruby Gupta, Akash Chinchole, Ngozi P. Paul…·Rajini Rao
This study shows that SPCA1 deficiency in keratinocytes disrupts actin dynamics and insulin signaling, leading to impaired migration and wound healing, and identifies potential therapeutic strategies.
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