Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism
Joseph F. Pierre, Diana La Torre, Ashley M. Sidebottom, Amal Kambal, Xiaorong Zhu, Yun Tao, Candace M. Cham, Ling Wang, Katharine G. Harris, Olga Y. Zaborina, John Alverdy, Herbert Herzog, Jessica N. Witchley, Suzanne M. Noble, Vanessa Leone, Eugene B. Chang
This paper identifies peptide YY (PYY) as a novel antimicrobial peptide produced by Paneth cells with selective antifungal activity against Candida albicans hyphae, maintaining gut fungal commensalism.
bioRxiv · May 15, 2020 · PreprintMolecular Biology