Amal Kambal

Streptococcus pneumoniae colonization modulates human nasal epithelial responses to respiratory syncytial virus infection

This study shows that Streptococcus pneumoniae precolonization reduces RSV levels and modulates epithelial transcriptional responses to RSV infection more than other nasal bacteria.

Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids

This study uses human nasal epithelial organoids to investigate how different bacteria colonize nasal tissue and induce cytokine responses, finding differential effects on chemokines and inflammasome signaling.

Human bladder organoids model urinary tract infection and bacteriophage therapy

This study develops human bladder organoids to model UTIs and phage therapy, showing phage reduces bacterial loads and inflammation during infection.

Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism

This paper identifies peptide YY (PYY) as a novel antimicrobial peptide produced by Paneth cells with selective antifungal activity against Candida albicans hyphae, maintaining gut fungal commensalism.