Author

Jessica N. Witchley

University of California, San FranciscoORCID 0000-0001-9859-3411Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Suzanne M. NobleiD· 2 shared Ali ToutiD· 1 shared Allon WagneriD· 1 shared Amal Kambal· 1 shared Andrew Ly· 1 shared Ashley M. SidebottomiD· 1 shared Candace M. ChamiD· 1 shared Cedric A. BrimacombeiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Suzanne M. NobleORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 29, 2026

Profiling of intestinal T cells reveals antigen-specific dependency on early-life programming for the generation of microbiota-reactive Tregs

Lara Vetter, Jessica N. Witchley, So Hyun Ahn…·Gregory M. Barton

This study profiles intestinal T cell responses to the microbiota, revealing antigen-specific dependencies on early-life programming for generating microbiota-reactive Tregs.

DOI 10.64898/2026.09.23.753882

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintMay 15, 2020

Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism

Joseph F. Pierre, Diana La Torre, Ashley M. Sidebottom…·Eugene B. Chang

This paper identifies peptide YY (PYY) as a novel antimicrobial peptide produced by Paneth cells with selective antifungal activity against Candida albicans hyphae, maintaining gut fungal commensalism.

2 citations

humanmetagenomics

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GeneticsbioRxivPreprintSep 6, 2018

Chromatin rewiring mediates programmed evolvability via aneuploidy

Cedric A. Brimacombe, Jordan E. Burke, Jahan‐Yar Parsa…·Suzanne M. Noble

The paper identifies a chromatin-based system in Candida albicans that enables inducible aneuploidy, linking chromatin regulation to antibiotic resistance and evolutionary adaptability.

3 citations

humanDNA methylation

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