Elevated MCOLN1 Expression in p53-Deficient Bladder Cancer is Necessary for Oncogene-Induced Cell proliferation, Inflammation, and Invasion
Jewon Jung, Han Liao, Hong Liang, John F. Hancock, Catherine Denicourt, Kartik Venkatachalam
This study shows that loss of p53 in bladder cancer increases MCOLN1 expression, which is necessary for HRAS-driven proliferation, inflammation, and invasion.
bioRxiv · Jul 8, 2020 · PreprintCancer Biology