Concerted neuron-astrocyte gene expression declines in aging and schizophrenia
Emi Ling, James C. Nemesh, Melissa Goldman, Nolan Kamitaki, Nora M. Reed, Robert E. Handsaker, Giulio Genovese, Jonathan S. Vogelgsang, Sherif Gerges, Seva Kashin, Sulagna Dia Ghosh, John M. Esposito, Kiely Morris, Daniel Meyer, Alyssa Lutservitz, , Steven A. McCarroll
The paper identifies a neuron-astrocyte gene expression program, SNAP, that declines in aging and schizophrenia, linking it to cognitive function and genetic risk factors.
Nature · Mar 6, 2024Peer-reviewedNeuroscience