Author

John Nolan

Buck Institute for Research on Aging

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ágnes KitteliD· 1 shared Andries ZijlstraiD· 1 shared Bo O. ZhouiD· 1 shared Clotilde ThéryiD· 1 shared Dolores Di VizioiD· 1 shared Edwin M. PosadasiD· 1 shared Elizabeth D. HutchinsiD· 1 shared Emily Y. KoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ágnes KittelORCID

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2 papers

Recent·Most cited

Senescent cells secrete chromatin components via senescence-associated extracellular particles

Peter D. Adams, Sviatlana Zaretski, Jose L. Nieto Torres, Xue Lei, John Nolan, Malene Hansen

This study shows senescent cells release chromatin components via extracellular particles, activating inflammation in neighboring cells and being present in aged mice.

bioRxiv · Dec 16, 2025 · PreprintCell Biology

Extracellular Vesicles heterogeneity through the lens of multiomics

Taylon Felipe Silva, Elizabeth D. Hutchins, Wenyan Zhao, Yari Ciani, Minhyung Kim, Emily Y. Ko, Javier Mariscal, Zhuyu Qiu, Fatima Bedier, Ágnes Kittel, Bo O. Zhou, Yang Wang, Megan C. Hall, Francesca I. Galasso, Rebecca A. Reiman, , Dolores Di Vizio

This study provides a multiomics resource of cancer extracellular vesicles, showing correlations between LO proteins and prostate cancer progression, and demonstrating the feasibility of single-cell RNA-Seq on EVs.

Cell Reports Medicine · Jun 6, 2025Peer-reviewedCancer Biology