Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein, TRIO
Alexandra Francian, Yevel Flores-García, John R. Powell, Nikolai Petrovsky, Fidel P. Zavala, Bryce Chackerian
This study develops a TRIO VLP vaccine targeting Anopheles mosquito salivary protein to enhance immunity against Plasmodium, showing strong antibody responses but limited protective efficacy in a malaria challenge model.
mSphere · Jan 29, 2025Peer-reviewedImmunology