Identification of Adjuvants that Enhance the Magnitude and Durability of Antibody Responses to a Nanoparticle-Based Malaria Vaccine
Yogesh Nepal, Alexandra Francian, Yevel Flores-Garcia…·Bryce Chackerian
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University of New MexicoORCID 0000-0003-4258-2283Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Yogesh Nepal, Alexandra Francian, Yevel Flores-Garcia…·Bryce Chackerian
Alexandra Francian, Srinivasa R. Gadam, Aidan Leyba…·Bryce Chackerian
This study compares IgG antibody titers in blood and dermal interstitial fluid after VLP-based vaccine immunization, finding similar titers and durability in both.
Aidan Leyba, Alexandra Francian, Mohammad Razjmoo…·Pavan Muttil
This study develops heat-stabilized dissolvable microneedles containing a novel VLP vaccine, showing robust immunogenicity and stability under extreme storage conditions.
Yogesh Nepal, Alexandra Francian, Yevel Flores-García…·Bryce Chackerian
This study evaluates virus-like particle vaccines targeting a specific CSP epitope, showing that structural context and adjuvant combinations enhance antibody responses and sterilizing immunity against malaria.
Alexandra Francian, Yevel Flores-García, John R. Powell…·Bryce Chackerian
This study develops a TRIO VLP vaccine targeting Anopheles mosquito salivary protein to enhance immunity against Plasmodium, showing strong antibody responses but limited protective efficacy in a malaria challenge model.